Shikari® (Q-CAN) Canakinumab ELISA

Enzyme immunoassay for the quantitative determination of Canakinumab (Ilaris®) in serum and plasma.

This kit has been especially developed for the quantitative determination of Canakinumab in serum and plasma samples between the Cmin and Cmax range of concentrations.

Canakinumab Drug Bank Accession Number is DB06168.

Canakinumab is a human interleukin-1β blocker and neutralizes its inflammatory activity by blocking its interaction with IL-1 receptors, but it does not bind IL-1alpha or IL-1 receptor antagonist (IL-1ra). Canakinumab is used to treat Periodic Fever Syndromes such as Cryopyrin-Associated Periodic Syndromes (CAPS) and Familial Mediterranean Fever (FMF), and also to treat active Systemic Juvenile Idiopathic Arthritis (SJIA). Measurement of biological drug trough levels and antibody to biological drug gained high importance during the course of treatment. These measurements enable dose adjustments and switch to another class of biological drug when necessary.

All SHIKARI® ELISA kits are suitable for biosimilar work.

Required Volume (µl)10Total Time (min)70SampleSerum, plasmaSample Number96Detection Limit (ng/mL)1Spike Recovery (%)Between 85-115Shelf Life (year)1Assay typeQuantitativeSpecies ReactivityHumanStorage conditionsStore at +4°C. Please refer to protocols.Shipping conditionsAt room temperature